|Project full title:||Tumor and Lymph Node on Chip for cancer studies|
|Grant Agreement no.:||953234|
|Duration in months:||48|
|Project funding:||5,77 M€ requested EU contribution|
|Funding scheme:||Research and Innovation action Lump Sum|
|Funding programme:||Horizon 2020|
|Free keywords:||Organ on Chip, Lymph Node, Tumor on chip, tumor migration, bioprinting,
Using sensitive proteomic and molecular approaches it will characterize the soluble signals that neutralize the immune response and allow tumor cells to metastasize to the LNs and to use them as spring boards for further dissemination. This will enable the use of existing drugs, or the development of new ones that could reverse this process and inhibit tumor growth and dissemination. It will also allow the identification of novel biomarkers characterizing metastatic cells which could also be exploited therapeutically. Moreover, by employing novel imaging approaches, Tumor-LN-oC will generate a spectral “fingerprint” of migrating/metastasizing cells which could be used for diagnostic purposes in tumor and lymph node biopsies.
- Verifiable progress in the application of Organ-on-Chip technologies for in-vitro research
- Reduction of the need for animal and clinical testing
- Lowering of barriers for application of Organ-on-Chip technology
- Improved competitiveness and attractiveness of the European biomedical and healthcare sector
- Increased awareness and knowledge about medical regulatory policies and requirements, especially by academics and SMEs
Tumor-LN-oC latest achievements will be observed, best dissemination channels for scientific, industrial and public awareness will be chosen and the outputs will be published in this section.
Project website launch – The document describes the creation of a comprehensive dedicated website for the project. This was be established at the beginning of the project and set up for public access. The website will be actively maintained during the project period.
First Press Release – After the project kicked off in May 2021 , the Tumor-LN-oC consortium published the project’s first press release on September 7th, 2021. It contains more information on the launch of the project, as well as its objectives and expected impact.
Factsheet/One-Pager – The factsheet provides general project information, a description of the Tumor-LN-oC ambition and expected impact as well as information on partners and project contacts.
Tumor-LN-oC kick-off meeting